Cartilage: Volume 2: Pathophysiology by Susanne Grässel, Attila Aszódi

By Susanne Grässel, Attila Aszódi

In 3 Volumes this mini ebook sequence offers present wisdom and new views on cartilage as a really good but flexible tissue. This moment quantity is devoted to uncomplicated pathologies of the 2 commonest osteoarticular illnesses affecting huge segments of the Western inhabitants, osteoarthritis and chondrodysplasias. This booklet addresses Professors, researchers and PhD scholars who're attracted to musculoskeletal and cartilage biology and pathobiology.

Show description

Read or Download Cartilage: Volume 2: Pathophysiology PDF

Similar orthopedics books

Fractures In Children

College of Texas, San Antonio. Fourth variation of a accomplished textual content on musculoskeletal accidents, for orthopedic surgeons and citizens. includes a significant switch within the structure - the hot and wide inclusion of particular operative suggestions. 30 members, 28 U. S. DNLM: Fractures - in infancy & formative years.

Practical Management of Pediatric and Adult Brachial Plexus Palsies: Expert Consult

Useful administration of Pediatric and grownup Brachial Plexus Palsies covers in-depth surgical ideas for dealing with issues of this important nerve complicated so you might so much successfully deal with accidents in sufferers of any age. Drs. Kevin Chung, Lynda Yan, and John McGillicuddy current a multidisciplinary method of pediatric brachial plexus damage therapy and rehabilitation, obstetric concerns, and different scorching subject matters within the box.

Air Instrument Surgery: Vol. 2: Orthopedics

Air software surgical procedure, quantity 2: Orthopedics has been compiled to help within the se­ lection and use of air tools in orthopedic surgical innovations. In every one example it makes an attempt to illustrate the vintage strategy, leaving it to the person health practitioner to enhance additional his services and ingenuity with air-driven tools.

Orthopaedic Basic Science : Foundations of Clinical Practice

The recent, fourth variation of Orthopaedic easy technology, built in partnership with the Orthopaedic learn Society, is your concise and clinically suitable source for the prognosis and therapy of musculoskeletal ailments and prerequisites. This thoroughly rewritten variation explains the services and barriers of the technological know-how in the back of the choices, remedies, and methods you practice on your perform each day.

Extra resources for Cartilage: Volume 2: Pathophysiology

Sample text

Arthritis Rheum 52(8):2386–2395. 21215 Lee W, Leddy HA, Chen Y, Lee SH, Zelenski NA, McNulty AL, Wu J, Beicker KN, Coles J, Zauscher S, Grandl J, Sachs F, Guilak F, Liedtke WB (2014) Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. Proc Natl Acad Sci U S A 111(47):E5114–E5122. 1414298111 Little CB, Barai A, Burkhardt D, Smith SM, Fosang AJ, Werb Z, Shah M, Thompson EW (2009) Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

Curr Drug Targets 11(5):599–613 Matthews GL, Hunter DJ (2011) Emerging drugs for osteoarthritis. Expert Opin Emerg Drugs 16(3):479–491. 576670 Mayan MD, Gago-Fuentes R, Carpintero-Fernandez P, Fernandez-Puente P, Filgueira-Fernandez P, Goyanes N, Valiunas V, Brink PR, Goldberg GS, Blanco FJ (2015) Articular chondrocyte network mediated by gap junctions: role in metabolic cartilage homeostasis. Ann Rheum Dis 74(1):275–284. 1136/annrheumdis-2013-204244 Messent EA, Ward RJ, Tonkin CJ, Buckland-Wright C (2007) Osteophytes, juxta-articular radiolucencies and cancellous bone changes in the proximal tibia of patients with knee osteoarthritis.

2  rticular Cartilage: Structure and Mechano-Sensing A Function The articular cartilage is a paucicellular type II collagen- and proteoglycan-rich tissue. It is a highly lubricated connective tissue with exceptionally low surface friction that allows smooth articulation of the opposing joint surfaces. Lubrication is achieved by a synergistic relationship between the proteoglycan, the lubricin and the glycosaminoglycan hyaluronan, together with phosphatidylcholine lipids (Seror et al. 2015). Intact lubrication protects the surface from shear stress.

Download PDF sample

Rated 4.39 of 5 – based on 23 votes