Cardiovascular Soft Tissue Mechanics by Stephen C. Cowin

By Stephen C. Cowin

The seven papers of this quantity current a glimpse into present examine on tender tissue mechanics in addition to a few destiny instructions. The seven papers main issue tissues in the cardiovascular approach: 3 specialise in arteries, 3 at the middle, and one on biaxial checking out of planar tissues similar to middle valves. on condition that heart problems is still the best explanation for dying within the built international, the significance of such study is obvious. There are remarkable universal positive factors of the seven papers. First, many of the proposed constitutive kin are prompted without delay through facts at the underlying microstructure, and particularly the orientations of a structurally vital protein (collagen) that types as undulated cross-linked fibers. one other function of lots of the papers is the honor of the truth that either arteries and the center comprise muscle and that there's a have to quantify the so-called energetic (contractile) reaction as well as the passive (non-contractile) reaction. Such relatives mustn't ever basically be structurally influenced, they need to eventually comprise the kinetics of calcium delivery within the muscle. Constitutive family for lively habit are mentioned within the majority of the papers. the expansion and reworking of cardiovascular tissues is one other universal function of the papers. over the past 20 years, separate advances in biochemistry, telephone biology, genetic engineering, and biomechanics have centred awareness at the ubiquitous position of development and reworking of tissues.

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B. A. edu 2 Medical Biophysics, University of Western Ontario, London, Ontario, Canada Received 20 April 2000; in revised form 13 February 2001 Abstract. Intracranial saccular aneurysms remain an enigma; it is not known why they form, why they enlarge, or why only some of them rupture. Nonetheless, there is general agreement that mechanics plays an essential role in each aspect of the natural history of these potentially deadly lesions. In this paper, we review recent findings that discount limit point instabilities under quasi-static increases in pressure and resonance under dynamic loading as possible mechanisms of enlargement of saccular aneurysms.

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