BioMEMS and Biomedical Nanotechnology: Biomolecular Sensing, by Rashid Bashir, Mauro Ferrari, Steven T. Wereley

By Rashid Bashir, Mauro Ferrari, Steven T. Wereley

Volume four of the multi-volume reference, BioMEMS and Biomedical Nanotechnology В is a balanced assessment of key features of BioMEMS sensors, together with (i) BioMEMS sensors and fabrics, (ii) technique of manipulating organic entities on the microscale, and (iii) micro-fluidics and characterization. those 3 sections supply a succinct evaluate of vital themes inside of a unmarried volume.

This quantity is particularly good illustrated with some of the figuresВ in color.

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Extra info for BioMEMS and Biomedical Nanotechnology: Biomolecular Sensing, Processing and Analysis

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This genetically engineered molecule was capable of being attached to a streptavidin monolayer and total internal reflection fluorescence was used to monitor the binding of a fluorescently labeled phosphorylcholine analog. Bioreceptor systems also used artificial membranes for many different applications. Stevens and coworkers have developed an artificial membrane by incorporating gangliosides into a matrix of diacetylenic lipids (5–10% of which were derivatized with sialic acid) [5]. The lipids were allowed to self-assemble into Langmuir-Blodgett layers and were then photopolymerized via ultraviolet irradiation into polydiacetylene membranes.

Cammann. Electroanalysis, 8:1135, 1996. P. F. Turner. Fresen. J. Anal. , 364:154, 1999. S. Sawata, E. Kai, K. Ikebukuro, T. Iida, T. Honda, and I. Karube. Biosens. , 14:397, 1999. A. Schmidt, C. StandfussGabisch, and U. Bilitewski. Biosens. , 11:1139, 1996. S. D. Green, Y, Yue, C. Nelson, F. Blattner, R. Sussman, and F. Cerrina. Nat. , 10:974, 1999. M. Song and T. Vo-Dinh. Anal. Bioanal. , 373:399, 2002. M. Song, J. Mobley, and T. Vo-Dinh. J. Chromatogra. B, 783:501, 2003. M. Song and T. Vo-Dinh.

Multiarray device. An optical microarray for the detection of toxic agents using a planar array of antibody probes was described by Ligler and coworkers [13]. Their system was composed of a CCD for detection, an excitation source and a microscope slide with a photoactivated optical adhesive. Antibodies against three different toxins, staphylococcal enterotoxin B (SEB), ricin, and Yersinia pestis, were covalently attached to small wells in the slide formed by the optical adhesive. The microscope slide was then mounted over the CCD with a gradient refractive index (GRIN) lens array used to focus the wells onto the CCD.

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