Antibiotic Resistance: Implications for Global Health and by Institute of Medicine, Board on Global Health, Forum on

By Institute of Medicine, Board on Global Health, Forum on Microbial Threats, Alison Mack, David A. Relman, Eileen R. Choffnes

Years of utilizing, misusing, and overusing antibiotics and different antimicrobial medicines has ended in the emergence of multidrug-resistant 'superbugs.' The IOM's discussion board on Microbial Threats held a public workshop April 6-7 to debate the character and assets of drug-resistant pathogens, the consequences for international healthiness, and the options to reduce the present and destiny influence of those superbugs.

Show description

Read or Download Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies: Workshop Summary PDF

Best allied health professions books

Coenzyme Q: Molecular Mechanisms in Health and Disease

Given that its discovery in 1957, Coenzyme Q has piqued the curiosity of scientists from quite a lot of disciplines as a result of its bioenergetics, vitamin-like habit, and interactions with antioxidant supplementations E and C. Coenzyme Q: Molecular Mechanisms in well-being and sickness is a accomplished treatise in this often-studied coenzyme.

Endoscopic Ear Surgery

Endoscopic concepts have revolutionized many surgical specialties and allowed the slow improvement of latest, minimally invasive techniques. Otology isn't any exception. the purpose of Endoscopic Ear surgical procedure is to discover the position of endoscopy within the evolution of otologic surgical procedure, and to introduce the healthcare professional to uncomplicated and complicated endoscopic ear surgical procedure recommendations.

Scientific Foundations of Audiology: Perspectives from Physics, Biology, Modeling, and Medicine

With developments throughout a number of clinical and clinical fields, execs in audiology are in a distinct place to combine state-of-the-art expertise with real-world events. clinical Foundations of Audiology presents a powerful foundation and philosophical framework for realizing a variety of domain names of listening to technology within the context of up to date advancements in genetics, gene expression, bioengineering, neuroimaging, neurochemistry, cochlear and mid-brain implants, linked speech processing and knowing, molecular biology, physics, modeling, drugs, and medical perform.

Additional resources for Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies: Workshop Summary

Sample text

Dichlorodiphenyltrichloroethane (DDT) was such a pesticide, Pimentel said, and like penicillin, its introduction after the end of World War II dramatically improved peoples’ lives. Originally used for malaria control, DDT was initially applied only to the insides of houses and huts for vector control, exposing about one mosquito in a million to the pesticide, he explained. Resistance to DDT did not appear until it came into widespread, uncontrolled, agricultural uses, thereby vastly increasing the numbers and types of insects directly or indirectly exposed to the insecticide.

That in nature antibiotics are not antibiotics and in nature resistance genes are not resistance genes,” he stated. Davies noted that antibiotic molecules have been found to promote a great variety of other activities, including recombination, horizontal gene transfer, mutation, metabolism, gene regulation, and signaling, all of which are mediated through cell receptors. Indeed, he added, most of the negative side-effects of antibiotic drugs stem from their interactions with a variety of human cell receptors.

Thus, the critical unit of AMR transmission is the resistance-associated gene or gene cassette, and the “vector” could be viewed alternatively as the microbial genome in which the gene or cassette is found, or the microbial community in which the resistant microbe resides, or the host or broader ecosystem that carries the community. Hospital-Acquired Infections Resistance poses a growing threat to the treatment and control of infectious diseases, including those that have long been endemic in human populations Copyright © National Academy of Sciences.

Download PDF sample

Rated 4.04 of 5 – based on 6 votes