Advances in Stereotactic and Functional Neurosurgery 6: by G. F. Rossi (auth.), Professor Jan Gybels, Professor Edward

By G. F. Rossi (auth.), Professor Jan Gybels, Professor Edward R. Hitchcock, Priv.-Doz. Christoph Ostertag, Professor Gian Franco Rossi, Professor Jean Siegfried, Professor Gabor Szikla (eds.)

Local interstitial radiation remedy of intrinsic and inaccessible mind tumors is faced with significant difficulties: 1. The tolerance of ordinary mind tissue, that's often taken with neighborhood tumor irradiation, i.e. perifocal white topic edema and demyelinating results, is essential. 2. info on radiation results of implanted radioactive assets on neoplastic tissue, i.e. info at the radiosensitivity and at the biology of tumors, are nonetheless broadly unavailable. In scientific perform the dose with which to accomplish a given quantity of tumor necrosis is approximately expected. This file offers with the experimental findings of Iodine-125 and Iridium-I92 everlasting implants in fit and neoplastic mind tissue. Our personal experimental findings are correlated with experimental info on Yttnul11-l)O irradiation from the literature. The examine is directed to assemble info at the tolerance non-tumoral mind tissue and to try to set up a dose-response courting. Morphologic adjustments within the puppy mind Following Interstitial Iodine-125 Irradiation Iodine-I25 seeds (manufactured by means of three M corporation, St. Paul, M. N.) with an job of 3.55 mCi have been completely implanted less than stereotactic stipulations into the subcortical white topic of the gyrus coronalis of the left hemisphere in 6 beagle canines. One animal with a non-radioactive seed implanted below comparable operative stipulations served as a keep watch over. The animals have been allowed to outlive 25, forty six, seventy one, ninety four, 248, 368 days, respectively, after the implantation. The keep an eye on animal survived forty six days. a close description of the experimental process is given in other places sixteen. 17.

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Extra info for Advances in Stereotactic and Functional Neurosurgery 6: Proceedings of the 6th Meeting of the European Society for Stereotactic and Functional Neurosurgery, Rome 1983

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2. , Praetorius, R. , Feature extraction from the encephalogram by adaptive segmentation. Proc. IEEE 65 (1977), 642--652. 3. Brazier, M. A. , Casby, 1. , Some application of correlation analysis to clinical problems in electroencephalography. Electroencephalography Clin. Neurophysiol. 8 (1956), 325-331. 4. Brazier, M. A. , Electrical activity recorded simultaneously from the scalp and deep structures of the human brain. 1. Nerv. Ment. Dis. 14711 (1968), 31-39. 32 H. G. Wieser: 5. Brazier, M. A.

Early Ocular Deviation (49 occipital seizures in 16 patients) TONIC - Controlateral Homolateral -- - - -- - - --,... Horizontal Oblique / SEIZURES PATIENTS 44 14 43 14 1 1 ----------------27 14 17 3 4 CLONIC Controlateral ----------- Horizontal TONIC-CLONIC Controlateral ----------- Horizontal 4 4 4 ----------------4 4 1 1 --------1 1 1 --------1 controlateral deviation, had a fifth seizure with a homolateral deviation. Most often (27 seizures, 14 patients) the eye movement was horizontal; in 3 patients (17 seizures) it was obliquely, upward, never downward.

The patients, although perfectly aware and conscious, were never able to control this deviation which was always opposite to the side of the ictal discharge. Only one patient, after 4 seizures with a Eye Movements and Occipital Seizures in Man 49 Table I. Early Ocular Deviation (49 occipital seizures in 16 patients) TONIC - Controlateral Homolateral -- - - -- - - --,... Horizontal Oblique / SEIZURES PATIENTS 44 14 43 14 1 1 ----------------27 14 17 3 4 CLONIC Controlateral ----------- Horizontal TONIC-CLONIC Controlateral ----------- Horizontal 4 4 4 ----------------4 4 1 1 --------1 1 1 --------1 controlateral deviation, had a fifth seizure with a homolateral deviation.

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